Research briefs

How can self-insured employers prepare for the portfolio impact of high-cost gene therapies coming to market?

Payer perspectives on outcomes tracking for value-based payment arrangements

The resource navigation challenges for patients and caregivers

Updated projection of US durable cell and gene therapies product-indication approvals

Federal Communication Guidelines

Financing Challenges for Solid-Tumor T-Cell Therapies

SYLK Medicaid Review

Expedited Insurance

Payer Perspectives Survey

Pediatric Gene Therapy Launches

Patient-Caregiver Financial Themes

Medicaid Best Price

Clinical trials and investment trends for novel CAR-T and TCR therapies

Model Contracts for Innovative Oncology Therapies

Role of COE networks in curative cellular oncology therapies

Stop-Loss Insurance or Reinsurance for Multiyear Contracts

Impact of Patient Mobility on Annuity/Performance-Based Contracting

Orphan Reinsurer Benefit Managers (ORBMs)

Impact of Actuarial Risk on Health Plans

Designing Precision Financing for Cures

Payer Segmentation for Precision Financing

Financing Mechanisms Payer Survey

Publications

Quinn, C., Ciarametaro, M., Sils, B., Phares, S., & Trusheim, M. (2023). Medicaid best price reforms to enable innovative payment models for cell and gene therapies. Expert Review of Pharmacoeconomics & Outcomes Research, 23(2), 191–203.

Young, C. M., Trusheim, M., & Quinn, C. (2022). Data for modelling US projections of product approvals, patients treated, and product revenues for durable cell and gene therapies. Data in Brief, 41, 107891.

C. Young; C. Quinn; M. Trusheim. Durable cell and gene therapy potential patient and financial impact: US projections of product approvals, patients treated, and product revenues. Drug Discovery Today (2021). DOI: 10.1016/j.drudis.2021.09.001

Ivica NA, Young CM. Tracking the CAR-T Revolution: Analysis of Clinical Trials of CAR-T and TCR-T Therapies for the Treatment of Cancer (1997–2020). Healthcare. 2021; 9(8):1062.

J.F. Barlow; M.W. Courtney; M. Trusheim. Payer Perspectives on Gene Therapy Reimbursement. Pharmaceutical Executive, 04/2020

J.F. Barlow; M.W. Courtney; M. Trusheim. Payer Perspectives on Reimbursement of One-Time High-Cost Durable Therapies. Pharmaceutical Executive, 01/09/2020

J.F. Barlow; M. Yang; R. Teagarden. Are Payers Ready, Willing, and Able to Provide Access to New Durable Gene Therapies? Value in Health, 06/2019, 10.1016/j.jval.2018.12.004

J. Barlow; R. Teagarden; M. Trusheim. Precision Financing of Durable, Potentially Curative Therapies. Pharmaceutical Executive, 01/2019

M.R. Trusheim; W.M. Cassidy; P.B. Bach. Alternative State-Level Financing for Hepatitis C Treatment—The "Netflix Model" JAMA, 10/29/2018, 10.1001

D. Han; D.S. Mytelka; G.L. Warren; M. Ciarametaro; M. Trusheim. Improving Management of Gene and Cell Therapies: The Orphan Reinsurer and Benefit Manager (ORBM). PharmaExec.com, 2018

M.R. Trusheim; A.A. Shrier; Z. Antonijevic; R.A. Beckman; R.K. Campbell; C. Chen; K.T. Flaherty; J. Loewy; D. Lacombe; S. Madhavan; H.P. Selker; L.J. Esserman. PIPELINEs: Creating Comparable Clinical Knowledge Efficiently by Linking Trial Platforms. Clinical Pharmacology & Therapeutics, 2016, 10.1002/cpt.514

R. Teagarden; T.F. Unger; G. Hirsch. Access and availability of orphan drugs in the United States: advances or cruel hoaxes? Expert Opinion on Orphan Drugs, 2014, 10.1517/21678707.2014.947265