What is BSR?
Biomedical breakthroughs are arriving faster than health systems can deliver them. The gap between what science can achieve and what patients actually receive — reliably, equitably, on time — is widening.
"It's like trying to drive a high-performance car through mud."
Senior Executive, Life Sciences Industry
BSR is the Center for Biomedical System Design's response: a multi-stakeholder initiative that builds the shared capabilities health ecosystems need to translate innovation into patient benefit at scale.
Drawing on nearly two decades of system-design work, BSR convenes biopharma, payers, providers, regulators, and patient advocates to redesign how breakthrough therapies reach the patients who need them most — and to measure whether they do.
BSR in Action
Alzheimer's disease
Transforming Early Alzheimer's Disease Care

Obesity
Transforming Obesity Disease Management

Accelerating and Scaling Impact
Biomedical Health Efficiency
Measuring What Determines System Readiness
Biomedical Health Efficiency (BHE) is the capacity of a system to deliver appropriate, timely, and equitable access to innovation with optimal use of resources:
- Makes system readiness measurable (not abstract)
- Identifies bottlenecks across regulation, payment, delivery, and access
- Enables comparison, benchmarking, and targeted intervention
If we can measure readiness,
we can improve—and accelerate—it
Dive deeper into BHE and how it relates to our Impact Acceleration Strategy.
Readiness Network
Scaling System Innovation
Transforming fragmented pilots into a new national action-learning-system change infrastructure. Learn more about how we are developing the System Readiness Network in our Impact Acceleration Strategy.
Scenario Planning Tool
Innovation Simulation Model for Alzheimer's Disease
An interactive tool for simulating the effect of combining solution designs laid out in the Early Alzheimer's Roadmap 2030.

