The approval of disease-modifying therapies for early, symptomatic Alzheimer's disease is raising hope for patients and caregivers. And promising new therapeutic and diagnostic capabilities are expected in the next five years. Unfortunately, the healthcare system is not prepared to serve all patients who might benefit from these innovations.

Our project focuses on one key leverage point in advancing health system preparedness in the US: reengineering Alzheimer's disease management (detection, diagnosis, and treatment) to be more primary care oriented.

Outputs from this project will include:

• Roadmap 2030, with a particular focus on transforming early Alzheimer’s disease care
• An open access dynamic simulation model ofAlzheimer’ disease for solution design and implementation planning
• Implementation plan for one selected system solution, demonstrating use of the simulation model
• Ongoing communication activities to enhance visibility and catalyze real-world adoption of solutions and tools across the global Alzheimer’s ecosystem.

Get the Executive Brief: Advancing System Readiness for Alzheimer’s Disease Breakthroughs