The LEAPS Project is advancing sustainable, patient-centered biomedical innovation through a new collaborative systems approach to the planning, production, and use of real-world evidence at the level of disease, not just a therapy. This two-part research brief series introduces the concept of “Downstream Innovation” as a critical enabler of such disease-ecosystem innovation. Part I outlines the concept of Downstream Innovation and describes strategic perspectives, and Part II applies the framework and principles to rheumatoid arthritis.

Downstream Innovation Part I: Strategic Perspectives and the Case for LEAPS
Downstream Innovation Part II: Real-World Discovery LEAPS to Life!